Violence has erupted across parts of Mexico following the killing of drug lord Nemesio Oseguera Cervantes, known as “El Mencho,” during a military operation in Jalisco State.

Oseguera, leader of the Jalisco New Generation Cartel (CJNG), died after being injured in clashes with security forces in Tapalpa on Sunday. The Defence Ministry said four cartel members were killed and three soldiers wounded.

In retaliation, suspected CJNG members set up roadblocks and burned vehicles in at least a dozen states, including in Guadalajara. Jalisco Governor Pablo Lemus Navarro declared a “code red,” suspending public transport and cancelling public activities.

Authorities reported about 250 roadblocks nationwide at the height of the unrest. At least 25 people were arrested, while shops and bank branches were attacked in several cities.

President Claudia Sheinbaum said federal and state agencies were working in close coordination and urged residents to remain calm.

Several airlines, including Air Canada, United Airlines, and American Airlines, cancelled flights to Jalisco, while the US and UK issued security warnings.

US officials confirmed intelligence support for the operation. White House Press Secretary Karoline Leavitt described Oseguera as a major target due to his role in fentanyl trafficking.

A former police officer, Oseguera led one of Mexico’s most powerful criminal networks for more than a decade. Authorities say security operations will continue to prevent further violence and restore order.